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Greater frequency of nut consumption is associated with lower prevalence of peripheral arterial disease


Reference:

Heffron SP et al. Greater frequency of nut consumption is associated with lower prevalence of peripheral arterial disease. Prev Med. 2015 Mar;72:15-8.


Abstract:

BACKGROUND: Nut consumption has been associated with lower risk of coronary heart disease and all-cause mortality. The association between nut intake and peripheral arterial disease (PAD) is uncertain.

OBJECTIVE: We sought to investigate the association between nut consumption and presence of prevalent PAD in a large cross-sectional sample.

METHODS: Self-referred participants at >20,000 US sites who completed a medical and lifestyle questionnaire were evaluated by screening ankle brachial indices for PAD. Multivariable logistic regression analysis was used to estimate odds of PAD in different nut consumption categories.

RESULTS: Among 3,312,403 individuals, mean age was 63.6 ± 10.6 years and 62.8% were female. There were 219,527 cases of PAD. After multivariable adjustment there was an inverse association of nut intake with PAD. Compared to subjects with consumption of nuts < once/month, daily nut consumption was associated with a 21% (95% CI 20%-23%) lower odds of having PAD.

CONCLUSION: These observations suggest the need for more rigorous testing evaluating the role of nuts in PAD prevention.

Belinda

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